5-Amino-1MQ – 5 mg

What is 5-Amino-1MQ?

5-Amino-1MQ (5-Amino-1-Methylquinolinium) is a small-molecule compound studied as a Nicotinamide N-methyltransferase (NNMT) inhibitor.

NNMT plays a role in cellular metabolism, fat storage, and energy regulation, making 5-Amino-1MQ of interest in metabolic and obesity research.

Structure

Compound Name: 5-Amino-1MQ
Chemical Class: Quinoline derivative / NNMT inhibitor

Molecular Formula: C₁₀H₁₀N₂⁺
Molecular Weight: ~158.2 g/mol (base ion)

Research

1. Metabolic Regulation

NNMT inhibition may enhance NAD⁺ availability and cellular energy expenditure.

2. Adiposity Studies

Preclinical models show reduced fat accumulation and improved lipid metabolism markers.

3. Insulin Sensitivity

Investigated for potential improvements in glucose handling and metabolic flexibility.

Future Research

Human metabolic safety, mitochondrial effects, and long-term weight regulation mechanisms remain under study.

Resources

• NNMT metabolic pathway research

• NAD⁺ metabolism and obesity studies

• Quinoline NNMT inhibitor development papers